Aceglatone

Aceglatone
Clinical data
Trade names Glucaron
AHFS/Drugs.com International Drug Names
ATC code none
Identifiers
Synonyms D-Glucaric acid di-γ-lactone 2,5-diacetate
2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone
2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone
CAS Number 642-83-1 N
PubChem (CID) 636372
ChemSpider 599998 YesY
UNII 347Q3OOJ13 YesY
ChEMBL CHEMBL2103781 N
Chemical and physical data
Formula C10H10O8
Molar mass 258.18 g/mol
3D model (Jmol) Interactive image
Melting point 185 to 186 °C (365 to 367 °F) [1]
 NYesY (what is this?)  (verify)

Aceglatone (Glucaron) is an antineoplastic drug available in Japan.[2]

It is an inhibitor of the enzyme β-glucuronidase.[3]

References

  1. Merck Index, 11th Edition, 20
  2. Glucaron, drugs.com
  3. Iida, Ryohei; Nagata, Sachiko; Kakimoto, Morio; Akaike, Hiroaki; Watanabe, Hiroko; Shioya, Akitoshi (1965). "2,5-Di-O-acetyl-D-glucosaccharo-(1→4)(6→3)-dilactone, a new potent β-glucuronidase inhibitor". Japanese Journal of Pharmacology. 15 (1): 88–90. doi:10.1254/jjp.15.88.


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