Bettie Steinberg
| Bettie M Steinberg | |
|---|---|
| Nationality | American |
| Education | University of California, Riverside, Adelphi University, SUNY Stony Brook |
| Occupation | Scientist |
| Employer | The Feinstein Institute for Medical Research |
| Known for | Medical Research |
| Website | |
Bettie M. Steinberg holds multiple positions within the North Shore-LIJ Health System: Chief Scientific Officer for The Feinstein Institute for Medical Research, Dean of the Elmezzi Graduate School of Molecular Medicine (both in Manhasset, NY), and Chair of the Department of Molecular Medicine at the Hofstra North Shore-LIJ School of Medicine in Hempstead, NY.[1][2]
Education
Dr. Bettie M. Steinberg did her undergraduate work at the University of California, Riverside, completing her degree in 1959. In 1967, she earned a master's degree in Biology from Adelphi University. In 1973, she returned to academia for her Ph.D. in microbiology, which she received from the State University of New York, Stony Brook in 1976 for her work on bacterial viruses. She then did a postdoctoral fellowship at SUNY Stony Brook, studying mammalian tumor viruses.
Academic Appointments
After her post doctoral fellowship, Steinberg moved to Columbia University, where she spent two years as a Senior Research Associate. She then joined the Department of Otolaryngology at Long Island Jewish Medical Center and joined The Feinstein Institute for Medical Research when it was established in 2000. She also holds academic appointments as Professor at the Elmezzi Graduate School;[3] Professor of Molecular Medicine and Otolaryngology at the Hofstra North Shore-LIJ School of Medicine;[2] Professor of Otorhinolaryngology – Head & Neck Surgery and Professor of Microbiology & Immunology at the Albert Einstein College of Medicine;[4] and Adjunct Associ ate Professor of Molecular Genetics and Microbiology and Adjunct Associate Professor of Oral Biology and Pathology at SUNY Stony Brook.[5]
Principal Scientific Contributions
When Dr. Steinberg arrived at Long Island Jewish Medical Center, she began her studies of human papillomaviruses (HPVs) and their role in diseases of the head and neck, especially recurrent respiratory papillomatosis. These studies have been supported continuously by grants from the National Institute of Health (NIH) since 1983. Dr. Steinberg, collaborating with Allan Abramson, M.D., discovered that HPVs establish latent infections, which are the source of recurrent disease.[6] Dr. Steinberg has dissected the molecular biology of papillomas, discovering that their signaling systems are altered in HPV infection and the cells don’t get the right messages to carry out their normal functions.,[7][8] They found that COX-2 is expressed in papillomas, and studied the potential of anti-inflammatory drugs as a treatment for respiratory papillomas. Dr. Steinberg and Dr. Abramson then did a preliminary treatment study on three patients with recurrent respiratory papillomas, and found that the papillomas stopped recurring during the two-year trial. A large clinical trial is currently in progress to continue this study.
Awards and Honors
- Robert K. Match Distinguished Scientist Award
- Long Island Achiever in Science Award from Long Island Center for Business and Professional Women
- Elliot Osserman Award from the Israel Cancer Research Fund
- Karl Storz Award from the American Society of Pediatric Oncology
- Lorinda de Roulet Award for Excellence in Research
- Israel Cancer Research Fund Award for Women of Excellence
- Science Achiever Award from the School-Business Partnerships of Long Island, Inc.
References
- ↑ "Research Pioneers at The Feinstein Institute". North Shore-LIJ Health System Foundation. Retrieved 5 August 2011.
- 1 2 "Molecular Medicine". Hofstra North Shore-LIJ School of Medicine. Retrieved 5 August 2011.
- ↑ "Elmezzi Faculty". The Elmezzi Graduate School of Molecular Medicine. Archived from the original on 26 July 2011. Retrieved 5 August 2011.
- ↑ "Faculty". Albert Einstein College of Medicine. Retrieved 5 August 2011.
- ↑ "Faculty & Staff by Department". Stony Brook University Medical Center. Retrieved 5 August 2011.
- ↑ "Latent Infection Induced with Cottontail Rabbit Papillomavirus: A Model for Human Papillomavirus Latency". American J Pathology. 144 (6): 1167–1171. 1994. PMC 1887472
. PMID 8203458. - ↑ "Up-regulation of Rac1 by Epidermal Growth Factor Mediates COX-2 Expression in Recurrent Respiratory Papillomas". Molecular Medicine. 13 (3-4): 143–50. 2007. doi:10.2119/2007-00005.Wu. PMC 1892765. PMID 17592548.
- ↑ "Pak1 and Pak2 are activated in recurrent respiratory papillomas, contributing to one pathway of Rac1-mediated COX-2 expression". International Journal of Cancer. 127 (9): 2230–7. 2010. doi:10.1002/ijc.25226. PMC 2932774. PMID 20131316.