Alpha-bisabolene synthase
Alpha-bisabolene synthase | |||||||||
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Identifiers | |||||||||
EC number | 4.2.3.38 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Alpha-bisabolene synthase (EC 4.2.3.38, bisabolene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-alpha-bisabolene-forming).[1] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate (E)-alpha-bisabolene + diphosphate
This synthase requires a divalent cation cofactor (Mg2+ or, to a lesser extent, Mn2+) to neutralize the negative charge of the diphosphate leaving group.
References
- ↑ Bohlmann, J.; Crock, J.; Jetter, R.; Croteau, R. (1998). "Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible (E)-α-bisabolene synthase from grand fir (Abies grandis)". Proc. Natl. Acad. Sci. USA. 95: 6756–6761. doi:10.1073/pnas.95.12.6756. PMC 22624. PMID 9618485.
External links
- Alpha-bisabolene synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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