CSN1S1

CSN1S1
Identifiers
Aliases	CSN1S1, CASA, CSN1, casein alpha s1
External IDs	HomoloGene: 48054 GeneCards: CSN1S1
Gene ontology Molecular function • transporter activity Cellular component • extracellular space • extracellular region Biological process • transmembrane transport • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1446	n/a
Ensembl	ENSG00000126545	n/a
UniProt	P47710	n/a
RefSeq (mRNA)	NM_001025104 NM_001890	n/a
RefSeq (protein)	NP_001020275.1 NP_001881.1	n/a
Location (UCSC)	Chr 4: 69.93 – 69.95 Mb	n/a
PubMed search	[1]	n/a
Wikidata

View/Edit Human

Alpha-S1-casein is a protein that in humans is encoded by the CSN1S1 gene.^[2][3][4]

Interactions

CSN1S1 has been shown to interact with SAP130.^[5]

References

1. "Human PubMed Reference:".
2. Fujiwara Y, Miwa M, Nogami M, Okumura K, Nobori T, Suzuki T, Ueda M (Mar 1997). "Genomic organization and chromosomal localization of the human casein gene family". Hum Genet. 99 (3): 368–73. doi:10.1007/s004390050374. PMID 9050925.
3. Johnsen LB, Rasmussen LK, Petersen TE, Berglund L (Aug 1995). "Characterization of three types of human alpha s1-casein mRNA transcripts". Biochem J. 309. ( Pt 1): 237–42. PMC 1135825. PMID 7619062.
4. "Entrez Gene: CSN1S1 casein alpha s1".
5. Menon, Suchithra; Tsuge Tomohiko; Dohmae Naoshi; Takio Koji; Wei Ning (2008). "Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome". BMC Biochem. England. 9: 1. doi:10.1186/1471-2091-9-1. PMC 2265268. PMID 18173839.

Further reading

• Takahashi M, Tomizawa K, Sato K, et al. (1995). "A novel tau-tubulin kinase from bovine brain.". FEBS Lett. 372 (1): 59–64. doi:10.1016/0014-5793(95)00955-9. PMID 7556643.
• Creasy CL, Chernoff J (1995). "Cloning and characterization of a human protein kinase with homology to Ste20.". J. Biol. Chem. 270 (37): 21695–700. doi:10.1074/jbc.270.37.21695. PMID 7665586.
• Chen CS, Bejcek BE, Kersey JH (1995). "A mapping study of 13 genes on human chromosome bands 4q11→q25.". Cytogenet. Cell Genet. 69 (3-4): 260–5. doi:10.1159/000133976. PMID 7698025.
• Cavaletto M, Cantisani A, Giuffrida G, et al. (1994). "Human alpha S1-casein like protein: purification and N-terminal sequence determination.". Biol. Chem. Hoppe-Seyler. 375 (2): 149–51. doi:10.1515/bchm3.1994.375.2.149. PMID 8192860.
• Murakami K, Lagarde M, Yuki Y (1999). "Identification of minor proteins of human colostrum and mature milk by two-dimensional electrophoresis.". Electrophoresis. 19 (14): 2521–7. doi:10.1002/elps.1150191427. PMID 9820977.
• Silljé HH, Takahashi K, Tanaka K, et al. (1999). "Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication.". EMBO J. 18 (20): 5691–702. doi:10.1093/emboj/18.20.5691. PMC 1171636. PMID 10523312.
• Menegay HJ, Myers MP, Moeslein FM, Landreth GE (2000). "Biochemical characterization and localization of the dual specificity kinase CLK1.". J. Cell. Sci. 113. ( Pt 18): 3241–53. PMID 10954422.
• Gray CW, Ward RV, Karran E, et al. (2000). "Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response.". Eur. J. Biochem. 267 (18): 5699–710. doi:10.1046/j.1432-1327.2000.01589.x. PMID 10971580.
• Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
• Kashiwaba M, Katsura K, Ohnishi M, et al. (2003). "A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9.". FEBS Lett. 538 (1-3): 197–202. doi:10.1016/S0014-5793(03)00153-4. PMID 12633878.
• Xu K, Ling MT, Wang X, Wong YC (2007). "Evidence of a novel biomarker, alphas1-Casein, a milk protein, in benign prostate hyperplasia.". Prostate Cancer Prostatic Dis. 9 (3): 293–7. doi:10.1038/sj.pcan.4500872. PMID 16683014.