Cortisol O-acetyltransferase
cortisol O-acetyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.27 | ||||||||
CAS number | 9076-48-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a cortisol O-acetyltransferase (EC 2.3.1.27) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + cortisol CoA + cortisol 21-acetate
Thus, the two substrates of this enzyme are acetyl-CoA and cortisol, whereas its two products are CoA and cortisol 21-acetate.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:cortisol O-acetyltransferase. Other names in common use include cortisol acetyltransferase, corticosteroid acetyltransferase, and corticosteroid-21-O-acetyltransferase.
References
- Thomas PJ (1968). "Cortisol acetyltransferase from baboon brain". Biochem. J. 109 (4): 695–6. PMC 1186958. PMID 4971640.
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