Cytokine adsorbing column

Cytokine-adsorbing columns remove inflammatory mediators from the body.[1] They are being studied in sepsis.[1] Specific products include the brand names Cytosorb by Cytosorbents and Lixelle among others.[1]

For the use of the procedure, it is necessary to channel the persons blood from the body and to let it circulate through the cartridge. It therefore can only be used in conjunction with an additional blood pump system, like a dialysis machine or a heart-lung machine.

The US Air Force is funding a $3million FDA approved randomized controlled trial in trauma and rhabdomyolysis.[2][3]

References

  1. 1 2 3 Honore, PM; Jacobs, R; Joannes-Boyau, O; De Regt, J; De Waele, E; van Gorp, V; Boer, W; Verfaillie, L; Spapen, HD (2013). "Newly designed CRRT membranes for sepsis and SIRS--a pragmatic approach for bedside intensivists summarizing the more recent advances: a systematic structured review.". ASAIO Journal. 59 (2): 99–106. doi:10.1097/mat.0b013e3182816a75. PMID 23438770.
  2. ↑ "Biotech Product Geared Toward Reducing Deaths in the ICU". Sentinel. Retrieved 9 April 2014.
  3. ↑ "Extracorporeal Therapy for the Removal of Myoglobin Using the CytoSorb in Patients With Rhabdomyolysis". clinicaltrials.gov. Retrieved 6 May 2014.
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