Dhori virus

Orthomyxoviridae
Virus classification
Group: Group V ((-)ssRNA)
Order: Unassigned
Family: Orthomyxoviridae
Genus: Thogotovirus
Species: Dhori virus
Serotypes

Batken virus
Dhori virus

Dhori virus (DHOV) is a species of the genus Thogotovirus and a member of the family Orthomyxoviridae. Its hosts are ticks, mosquitoes, and mammals (including humans). Dhori virus is lethal to mice, causing systemic pathologic changes similar to those reported in humans with virulent influenza A (H5N1) virus infection.[1]

Batken virus (BKNV) is considered a subtype of Dhori virus. Serological cross-reactions between Batken and Dhori viruses indicate a phylogenetic relationship between these viruses.[2]

References

  1. Li G, Wang N, Guzman H, Sbrana E, Yoshikawa T, Tseng CT, Tesh RB, Xiao SY. Dhori virus (Orthomyxoviridae: Thogotovirus) infection of mice produces a disease and cytokine response pattern similar to that of highly virulent influenza A (H5N1) virus infection in humans. Am J Trop Med Hyg. 2008 Apr;78(4):675–80. PubMed PMID 18385368.
  2. Frese M, Weeber M, Weber F, Speth V, Haller O. Mx1 sensitivity: Batken virus is an orthomyxovirus closely related to Dhori virus. J Gen Virol. 1997 Oct;78 (Pt 10):2453–8. PubMed PMID 9349464.
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