Dolichyl-phosphatase

This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. The systematic name of this enzyme class is dolichyl-phosphate phosphohydrolase. Other names in common use include dolichol phosphate phosphatase, dolichol phosphatase, dolichol monophosphatase, dolichyl monophosphate phosphatase, dolichyl phosphate phosphatase, polyisoprenyl phosphate phosphatase, polyprenylphosphate phosphatase, and Dol-P phosphatase. This enzyme participates in n-glycan biosynthesis.

References

Adrian GS, Keenan RW (1979). "A dolichyl phosphate-cleaving acid phosphatase from Tetrahymena pyriformis". Biochim. Biophys. Acta. 575 (3): 431–8. doi:10.1016/0005-2760(79)90112-7. PMID 229909.
Rip JW, Rupar CA, Chaudhary N, Carroll KK (1981). "Localization of a dolichyl phosphate phosphatase in plasma membranes of rat liver". J. Biol. Chem. 256 (4): 1929–34. PMID 6257694.
Wedgwood JF, Strominger JL (1980). "Enzymatic activities in cultured human lymphocytes that dephosphorylate dolichyl pyrophosphate and dolichyl phosphate". J. Biol. Chem. 255 (3): 1120–3. PMID 6243292.

Hydrolase: esterases (EC 3.1)

3.1.1: Carboxylic
ester hydrolases

Lipase

Phospholipase
- A1
- A2
- B

3.1.2: Thioesterase

3.1.3: Phosphatase

3.1.4: Phosphodiesterase

3.1.6: Sulfatase

Nuclease (includes
deoxyribonuclease and
ribonuclease)

3.1.11-16: Exonuclease

Exodeoxyribonuclease	RecBCD

Exoribonuclease	Oligonucleotidase

3.1.21-31: Endonuclease

Endodeoxyribonuclease	Deoxyribonuclease I Deoxyribonuclease II Deoxyribonuclease IV Restriction enzyme UvrABC endonuclease

Endoribonuclease	RNase III RNase H 1 2A 2B 2C RNase P RNase A 1 2 3 4/5 RNase T1 RNA-induced silencing complex

either deoxy- or ribo-	Aspergillus nuclease S1 Micrococcal nuclease

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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