Dyskeratosis

Dyskeratosis is abnormal keratinization occurring prematurely within individual cells or groups of cells below the stratum granulosum.^[1]

Dyskeratosis congenita is congenital disease characterized by reticular skin pigmentation, nail degeneration, and leukoplakia on the mucous membranes associated with short telomeres.^[2]

References

↑ Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) Robbins & Cotran Pathologic Basis of Disease (8th ed.). Saunders. Page 1392. ISBN 0-7216-0187-1.
↑ Mason PJ, Bessler M (2011). "The genetics of dyskeratosis congenita". CANCER GENETICS. 204 (12): 635–645. doi:10.1016/j.cancergen.2011.11.002. PMC 3269008. PMID 22285015.

Macroscopic

Primary lesions	flat Macule Patch elevated Papule Nodule Plaque fluid Vesicle Bulla Pustule Ulcer Erosion Telangiectasia Special initial lesions : Burrow Tunnel Comedo Scutulum Target lesion Herald patch Wheal

Secondary lesions	Scale Crust Lichenification Excoriation Induration Atrophy

Microscopic

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