ELF1

ELF1
Identifiers
Aliases ELF1
External IDs MGI: 107180 HomoloGene: 7303 GeneCards: ELF1
Genetically Related Diseases
systemic lupus erythematosus[1]
Orthologs
Species Human Mouse
Entrez

1997

13709

Ensembl

ENSG00000120690

ENSMUSG00000036461

UniProt

P32519

Q60775

RefSeq (mRNA)

NM_001145353
NM_172373

NM_001286411
NM_001286412
NM_007920

RefSeq (protein)

NP_001138825.1
NP_758961.1

NP_001273340.1
NP_031946.1

Location (UCSC) Chr 13: 40.93 – 41.06 Mb Chr 14: 79.48 – 79.58 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

E74-like factor 1 (ets domain transcription factor) is a protein that in humans is encoded by the ELF1 gene.[4]

Function

This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants.[4]

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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