FRS3

FRS3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases FRS3, FRS2-beta, FRS2B, FRS2beta, SNT-2, SNT2, fibroblast growth factor receptor substrate 3
External IDs MGI: 2135965 HomoloGene: 4845 GeneCards: FRS3
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

10817

107971

Ensembl

ENSG00000137218

ENSMUSG00000023266

UniProt

O43559

Q91WJ0

RefSeq (mRNA)

NM_006653

NM_144939

RefSeq (protein)

NP_006644.1

NP_659188.1

Location (UCSC) Chr 6: 41.77 – 41.79 Mb Chr 17: 47.69 – 47.7 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Fibroblast growth factor receptor substrate 3 is a protein that in humans is encoded by the FRS3 gene.[3][4][5]

The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras.[5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Wang JK, Xu H, Li HC, Goldfarb M (Oct 1996). "Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras". Oncogene. 13 (4): 721–9. PMID 8761293.
  4. Xu H, Lee KW, Goldfarb M (Aug 1998). "Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins". J Biol Chem. 273 (29): 17987–90. doi:10.1074/jbc.273.29.17987. PMID 9660748.
  5. 1 2 "Entrez Gene: FRS3 fibroblast growth factor receptor substrate 3".

Further reading


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