Diflorasone
Clinical data | |
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Trade names | Psorcon |
AHFS/Drugs.com | Monograph |
MedlinePlus | a602019 |
Pregnancy category |
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Routes of administration | Topical |
ATC code | D07AC10 (WHO) |
Legal status | |
Legal status |
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Identifiers | |
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CAS Number | 2557-49-5 |
PubChem (CID) | 71414 |
IUPHAR/BPS | 7068 |
DrugBank | DB00223 |
ChemSpider | 64504 |
UNII | T2DHJ9645W |
KEGG | D01327 |
ChEBI | CHEBI:31483 |
ChEMBL | CHEMBL1201380 |
ECHA InfoCard | 100.018.069 |
Chemical and physical data | |
Formula | C26H32F2O7 |
Molar mass | 494.525 g/mol |
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Diflorasone is a topical steroid that comes in the form of a cream containing diflorasone diacetate. In is manufactured by E. Fougera & Co. and is used as an anti-inflammatory and anti-itching agent, like other topical corticosteroids. It is prescribed for psoriasis[1] and atopic dermatitis, among other conditions. With respect to potency, it is regarded as a Class I steroid (of classes I–IV).[2]
No long-term animal studies have been done to determine whether diflorasone could have carcinogenic properties.
Little data is available regarding whether diflorasone would be present in great enough quantities to cause harm to an infant.[3]
References
- ↑ Shupack, J. L.; Jondreau, L.; Kenny, C.; Stiller, M. J. (1993). "Diflorasone diacetate ointment 0.05% versus betamethasone dipropionate ointment 0.05% in moderate-severe plaque-type psoriasis". Dermatology (Basel, Switzerland). 186 (2): 129–132. PMID 8428041.
- ↑ psoriasis.org: [www.psoriasis.org/sublearn03_mild_potency]
- ↑ Drugs.com: Diflorasone topical
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