Benzthiazide

Benzthiazide
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
ATC code none
Legal status
Legal status
  • ℞ (Prescription only)
Pharmacokinetic data
Bioavailability 60 to 70%
Protein binding 30%
Biological half-life 5 to 15 hours
Excretion Renal
Identifiers
CAS Number 91-33-8 YesY
PubChem (CID) 2343
IUPHAR/BPS 7125
DrugBank DB00562 YesY
ChemSpider 2253 YesY
UNII 1TD8J48L61 YesY
KEGG D00651 YesY
ChEBI CHEBI:3047 YesY
ChEMBL CHEMBL1201039 N
Chemical and physical data
Formula C15H14ClN3O4S3
Molar mass 431.94 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Benzthiazide (BAN/INN, also known as benzothiazide; trade names Aquatag, Dihydrex, Diucen, Edemax, Exna, Foven and others[1]) is a thiazide diuretic used in the treatment of high blood pressure and edema. It is no longer available in the United States.

In the United Kingdom, it was also sold in combination with the potassium-sparing diuretic triamterene under the trade name Dytide.[2] The same combination is still available in Switzerland as Dyrenium compositum.[3]

References

  1. David J. Triggle; C. R. Ganellin; F. MacDonald (1996). Dictionary of Pharmacological Agents. 1. Boca Raton: Chapman & Hall/CRC. p. 246. ISBN 0-412-46630-9. Retrieved on August 29, 2008 through Google Book Search.
  2. "Triamterene and Benzthiazide". PatientUK. 2005. Retrieved 2008-08-29.
  3. "Dyrenium compositum". Doetsch Grether. n.d. Archived from the original on February 11, 2007. Retrieved 2008-08-29.


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