GPAM

GPAM
Identifiers
Aliases GPAM, GPAT, GPAT1, glycerol-3-phosphate acyltransferase, mitochondrial
External IDs MGI: 109162 HomoloGene: 7343 GeneCards: GPAM
Orthologs
Species Human Mouse
Entrez

57678

14732

Ensembl

ENSG00000119927

ENSMUSG00000024978

UniProt

Q9HCL2

Q61586

RefSeq (mRNA)

NM_001244949
NM_020918

NM_008149

RefSeq (protein)

NP_001231878.1
NP_065969.3

NP_032175.2

Location (UCSC) Chr 10: 112.15 – 112.22 Mb Chr 19: 55.07 – 55.1 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Glycerol-3-phosphate acyltransferase 1, mitochondrial is an enzyme that in humans is encoded by the GPAM gene.[3][4][5]

Glycerol-3-phosphate acyltransferase (GPAT; EC 2.3.1.15), which catalyzes the initial and committing step in glycerolipid biosynthesis, is predicted to play a pivotal role in the regulation of cellular triacylglycerol and phospholipid levels. Two mammalian forms of GPAT have been identified on the basis of localization to either the endoplasmic reticulum or mitochondria.[supplied by OMIM][5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O (Dec 2000). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877.
  4. Yet SF, Lee S, Hahm YT, Sul HS (Oct 1993). "Expression and identification of p90 as the murine mitochondrial glycerol-3-phosphate acyltransferase". Biochemistry. 32 (36): 9486–9491. doi:10.1021/bi00087a029. PMID 8369314.
  5. 1 2 "Entrez Gene: GPAM glycerol-3-phosphate acyltransferase, mitochondrial".

Further reading


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