Glycoside hydrolase family 77
| Glyco_hydro_77 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 structure determination and refinement at 1.8 a resolution of disproportionating enzyme from potato | |||||||||
| Identifiers | |||||||||
| Symbol | Glyco_hydro_77 | ||||||||
| Pfam | PF02446 | ||||||||
| Pfam clan | CL0058 | ||||||||
| InterPro | IPR003385 | ||||||||
| SCOP | 1cwy | ||||||||
| SUPERFAMILY | 1cwy | ||||||||
| CAZy | GH77 | ||||||||
| |||||||||
In molecular biology, glycoside hydrolase family 77 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site,[4] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[5]
The enzymes in this family have amylomaltase or 4-α-glucanotransferase activity (EC 2.4.1.25) CAZY GH_77, they transfer a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.[6] They belong to the disproportionating family of enzymes.
References
- ↑ Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G (1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. doi:10.1073/pnas.92.15.7090. PMC 41477
. PMID 7624375. - ↑ Henrissat B, Davies G (1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–859. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
- ↑ Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.
- ↑ Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999.
- ↑ CAZypedia, an online encyclopedia of carbohydrate-active enzymes.
- ↑ Okada S, Takaha T, Yanase M, Smith SM (1993). "Disproportionating enzyme (4-alpha-glucanotransferase; EC 2.4.1.25) of potato. Purification, molecular cloning, and potential role in starch metabolism". J. Biol. Chem. 268 (2): 1391–1396. PMID 7678257.
This article incorporates text from the public domain Pfam and InterPro IPR003385