Granulibacter bethesdensis
| Granulibacter bethesdensis | |
|---|---|
| Scientific classification | |
| Kingdom: | Bacteria |
| Phylum: | Proteobacteria |
| Class: | Alphaproteobacteria |
| Order: | Rhodospirillales |
| Family: | Acetobacteraceae |
| Genus: | Granulibacter |
| Species: | Granulibacter bethesdensis Greenberg et al. 2006 |
Granulibacter bethesdensis is a Gram-negative, aerobic coccobacillus to rod-shaped, non-motile, catalase-positive and oxidase-negative bacteria first described in 2006 by Dr. Steve Holland's team at the National Institutes of Health in Bethesda, Maryland.[1]
Clinical Significance
Granulibacter bethesdensis was identified in a series of patients with chronic granulomatous disease (CGD).[1] In a later study, nearly half of patients with CGD tested and a quarter of healthy volunteers showed some immunoreactivity to Granulibacter bethesdensis, suggesting infections with this organism occur more often than it is isolated.[2]
References
- 1 2 Greenberg, DE; Porcella SF; Stock F; Wong A; Conville PS; Murray PR; Holland SM; Zelazny AM (Nov 2006). "Granulibacter bethesdensis gen. nov., sp. nov., a distinctive pathogenic acetic acid bacterium in the family Acetobacteraceae". Int J Syst Evol Microbiol. Pt 11. 56: 2609–16. doi:10.1099/ijs.0.64412-0. PMID 17082400.
- ↑ Greenberg, DE; Shoffner AR; Marshall-Batty KR; Arora K; Zhao M; Martin R; Ding L; Hammer CH; Shaw PA; Kuhns DB; Malech HL; Gallin JI; Zarember KA; Holland SM (Sep 2012). "Serologic reactivity to the emerging pathogen Granulibacter bethesdensis". J Infect Dis. 2006. 15 (6): 943–51. doi:10.1093/infdis/jis431. PMC 3501152
. PMID 22782953.
External links
- LPSN
- Granulibacter bethesdensis at the Encyclopedia of Life
- Type strain of Granulibacter bethesdensis at BacDive - the Bacterial Diversity Metadatabase
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