Granulomatous prostatitis

Granulomatous prostatitis
Micrograph showing a granulomatous prostatitis due to BCG treatment for bladder cancer. H&E stain.
Classification and external resources

Granulomatous prostatitis is an uncommon disease of the prostate, an exocrine gland of the male reproductive system. It is a form of prostatitis, i.e. inflammation of the prostate, resulting from infection (bacterial, viral, or fungal), the BCG therapy, malacoplakia or systemic granulomatous diseases which involve the prostate.

Pathogenesis of granulomatous prostatitis

Prostatic secretions escape into the stroma and elicit an inflammatory response.

Histopathology of granulomatous prostatitis

Noticeable destruction of Acini, surrounded by epitheloid cells, giant cells, lymphocytes, plasma cells and dense fibrosis.