2-hydroxychromene-2-carboxylate isomerase
| 2-hydroxychromene-2-carboxylate isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.99.1.4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2-hydroxychromene-2-carboxylate isomerase (EC 5.99.1.4, HCCA isomerase, 2HC2CA isomerase, 2-hydroxychromene-2-carboxylic acid isomerase) is an enzyme with systematic name 2-hydroxy-2H-chromene-2-carboxylate---(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate isomerase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- 2-hydroxy-2H-chromene-2-carboxylate (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate
This enzyme is involved in naphthalene degradation.
References
- ↑ Ohmoto, T.; Kinoshita, T.; Moriyoshi, K.; Sakai, K.; Hamada, N.; Ohe, T. (1998). "Purification and some properties of 2-hydroxychromene-2-carboxylate isomerase from naphthalenesulfonate-assimilating Pseudomonas sp. TA-2". J. Biochem. 124 (3): 591–597. doi:10.1093/oxfordjournals.jbchem.a022152. PMID 9722670.
- ↑ Keck, A.; Conradt, D.; Mahler, A.; Stolz, A.; Mattes, R.; Klein, J. (2006). "Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6". Microbiology. 152: 1929–1940. doi:10.1099/mic.0.28783-0. PMID 16804169.
- ↑ Eaton, R.W. (1994). "Organization and evolution of naphthalene catabolic pathways: sequence of the DNA encoding 2-hydroxychromene-2-carboxylate isomerase and trans-o-hydroxybenzylidenepyruvate hydratase-aldolase from the NAH7 plasmid". J. Bacteriol. 176 (24): 7757–7762. PMID 8002605.
- ↑ Thompson, L.C.; Ladner, J.E.; Codreanu, S.G.; Harp, J.; Gilliland, G.L.; Armstrong, R.N. (2007). "2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomonas putida". Biochemistry. 46 (23): 6710–6722. doi:10.1021/bi700356u. PMID 17508726.
External links
- 2-hydroxychromene-2-carboxylate isomerase at the US National Library of Medicine Medical Subject Headings (MeSH)
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