HNE
HNE may refer to:
- Hne, a Burmese musical instrument
- 4-Hydroxynonenal, produced by lipid peroxidation
- Chhattisgarhi language, spoken in India
- Hexanitroethane, an oxidizer
- Historic New England, an American historical society
- Home News Enterprises, an American publisher
- Michel Hne, New Caledonian football player
- Neutrophil elastase
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