HOOK3

HOOK3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases HOOK3, HK3, hook microtubule-tethering protein 3
External IDs MGI: 2443554 HomoloGene: 13022 GeneCards: HOOK3
Orthologs
Species Human Mouse
Entrez

84376

320191

Ensembl

ENSG00000168172

ENSMUSG00000037234

UniProt

Q86VS8

Q8BUK6

RefSeq (mRNA)

NM_032410

NM_207659

RefSeq (protein)

NP_115786.1

NP_997542.1

Location (UCSC) Chr 8: 42.9 – 43.03 Mb Chr 8: 26.02 – 26.12 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Protein Hook homolog 3 is a protein that in humans is encoded by the HOOK3 gene.[3][4]

Function

Hook proteins are cytosolic coiled coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[4]

References

Further reading


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