IFIT2

IFIT2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases IFIT2, G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, P54, cig42, interferon induced protein with tetratricopeptide repeats 2
External IDs MGI: 99449 HomoloGene: 1187 GeneCards: IFIT2
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

3433

15958

Ensembl

ENSG00000119922

ENSMUSG00000045932

UniProt

P09913

Q64112

RefSeq (mRNA)

NM_001547

NM_008332

RefSeq (protein)

NP_001538.4

NP_032358.1

Location (UCSC) Chr 10: 89.3 – 89.31 Mb Chr 19: 34.55 – 34.58 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Interferon-induced protein with tetratricopeptide repeats 2 or IFIT2 is a protein found in humans which is encoded by the IFIT2 gene.[3][4][5]

Clinical significance

IFIT2 may play a role in prevention of tumor progression.[6]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Wathelet MG, Szpirer J, Nols CB, Clauss IM, De Wit L, Islam MQ, Levan G, Horisberger MA, Content J, Szpirer C (Nov 1988). "Cloning and chromosomal location of human genes inducible by type I interferon". Somat Cell Mol Genet. 14 (5): 415–26. doi:10.1007/BF01534709. PMID 3175763.
  4. Wathelet MG, Clauss IM, Content J, Huez GA (Jun 1988). "The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family". FEBS Lett. 231 (1): 164–71. doi:10.1016/0014-5793(88)80724-5. PMID 3360121.
  5. "Entrez Gene: IFIT2 interferon-induced protein with tetratricopeptide repeats 2".
  6. Lai KC, Chang KW, Liu CJ, Kao SY, Lee TC (2008). "IFN-induced protein with tetratricopeptide repeats 2 inhibits migration activity and increases survival of oral squamous cell carcinoma". Mol. Cancer Res. 6 (9): 1431–9. doi:10.1158/1541-7786.MCR-08-0141. PMID 18819931.

Further reading


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