ITGB1BP3

NMRK2
Identifiers
Aliases	NMRK2, ITGB1BP3, MIBP, NRK2, nicotinamide riboside kinase 2
External IDs	MGI: 1916814 HomoloGene: 113783 GeneCards: NMRK2
EC number	2.7.1.173
Gene ontology Molecular function • transferase activity • nucleotide binding • protein binding • ATP binding • metal ion binding • ribosylnicotinamide kinase activity • kinase activity Cellular component • intracellular Biological process • pyridine nucleotide biosynthetic process • negative regulation of myoblast differentiation • NAD biosynthetic process • phosphorylation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27231	69564
Ensembl	ENSG00000077009	ENSMUSG00000004939
UniProt	Q9NPI5	Q9D7C9
RefSeq (mRNA)	NM_001289117 NM_014446 NM_170678	NM_027120
RefSeq (protein)	NP_001276046.1 NP_733778.1	NP_081396.1
Location (UCSC)	Chr 19: 3.93 – 3.94 Mb	Chr 10: 81.2 – 81.2 Mb
PubMed search	[1]	[2]
Wikidata

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Nicotinamide riboside kinase 2 is an enzyme that in humans is encoded by the ITGB1BP3 gene.^[3][4][5]

Interactions

ITGB1BP3 has been shown to interact with ST7.^[6]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Li J, Mayne R, Wu C (Feb 2000). "A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation". J Cell Biol. 147 (7): 1391–8. doi:10.1083/jcb.147.7.1391. PMC 2174245. PMID 10613898.
4. Bieganowski P, Brenner C (May 2004). "Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans". Cell. 117 (4): 495–502. doi:10.1016/S0092-8674(04)00416-7. PMID 15137942.
5. "Entrez Gene: ITGB1BP3 integrin beta 1 binding protein 3".
6. Battle, Michele A; Maher Veronica M; McCormick J Justin (Jun 2003). "ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways". Biochemistry. United States. 42 (24): 7270–82. doi:10.1021/bi034081y. ISSN 0006-2960. PMID 12809483.

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Li J, Rao H, Burkin D, et al. (2003). "The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition.". Dev. Biol. 261 (1): 209–19. doi:10.1016/S0012-1606(03)00304-X. PMID 12941630.
• Battle MA, Maher VM, McCormick JJ (2003). "ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways.". Biochemistry. 42 (24): 7270–82. doi:10.1021/bi034081y. PMID 12809483.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.