Imidafenacin

Imidafenacin
Clinical data

Routes of administration	Oral
ATC code	none
Legal status
Legal status	℞ (Prescription only)
Identifiers
IUPAC name 4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide
CAS Number	170105-16-5^Y
PubChem (CID)	6433090
ChemSpider	4938278^N
UNII	XJR8Y07LJO^Y
ChEMBL	CHEMBL53366^N
ECHA InfoCard	100.216.585
Chemical and physical data
Formula	C₂₀H₂₁N₃O
Molar mass	319.40 g/mol
3D model (Jmol)	Interactive image
SMILES CC1=NC=CN1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N
InChI InChI=1S/C20H21N3O/c1-16-22-13-15-23(16)14-12-20(19(21)24,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,13,15H,12,14H2,1H3,(H2,21,24)^N Key:SQKXYSGRELMAAU-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Imidafenacin (INN) is a urinary antispasmodic of the anticholinergic class. Its molecular weight is 319.40 g/mol

References

Kobayashi F, Yageta Y, Segawa M, Matsuzawa S (2007). "Effects of imidafenacin (KRP-197/ONO-8025), a new anti-cholinergic agent, on muscarinic acetylcholine receptors. High affinities for M3 and M1 receptor subtypes and selectivity for urinary bladder over salivary gland". Arzneimittelforschung. 57 (2): 92–100. doi:10.1055/s-0031-1296589. PMID 17396619.
Miyachi H, Kiyota H, Uchiki H, Segawa M (June 1999). "Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents". Bioorg. Med. Chem. 7 (6): 1151–61. doi:10.1016/S0968-0896(99)00003-6. PMID 10428387.

Urologicals, including antispasmodics (G04B)

Acidifiers	Ammonium chloride Calcium chloride

Urinary antispasmodics (primarily antimuscarinics)	Darifenacin Emepronium Fesoterodine Flavoxate Imidafenacin Meladrazine Mirabegron Oxybutynin Propiverine Solifenacin Terodiline Tolterodine Trospium chloride

Other urologicals	Urea analogues: Acetohydroxamic acid Salicylhydroxamic acid Other: Collagen Dimethyl sulfoxide Magnesium hydroxide Pentosan polysulfate Phenazopyridine Phenyl salicylate Succinimide

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