KLK13

KLK13
Identifiers
Aliases KLK13, KLK-L4, KLKL4, kallikrein related peptidase 13
External IDs MGI: 3615275 HomoloGene: 56714 GeneCards: KLK13
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

26085

626834

Ensembl

ENSG00000167759

ENSMUSG00000054046

UniProt

Q9UKR3
Q5BQ95
Q5BQ97

n/a

RefSeq (mRNA)

NM_015596

NM_001039042

RefSeq (protein)

NP_056411.1

n/a

Location (UCSC) Chr 19: 51.06 – 51.07 Mb Chr 7: 43.71 – 43.73 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Kallikrein-13 is a protein that in humans is encoded by the KLK13 gene.[3][4][5]

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined.[5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, Stephan C, Talieri M, Yousef GM (Jun 2006). "A comprehensive nomenclature for serine proteases with homology to tissue kallikreins". Biol Chem. 387 (6): 637–41. doi:10.1515/BC.2006.082. PMID 16800724.
  4. Diamandis, Eleftherios P.; Deperthes, David; Lundwall, Åke (Jun 2006). "Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005". Biol Chem. 387 (6): 635–824. doi:10.1515/BC.2006.081. PMID 16800723.
  5. 1 2 "Entrez Gene: KLK13 kallikrein-related peptidase 13".

Further reading

External links


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