Kalappa Muniyappa

Kalappa Muniyappa
Born (1952-09-08)September 8, 1952
Karnataka, India
Residence Karnataka, India
Nationality Indian
Fields
Institutions
Alma mater
Known for Molecular basis of homologous genetic recombination
Notable awards 1980 Hanumantha Rao Memorial Medal
1992 Rockefeller Foundation Career Development Award
1994 IISc M. Sreenivasaya Memorial Award
1995 Shanti Swarup Bhatnagar Prize
1995 ACS Eleanor Roosevelt Award
1999 Yamagiwa International Cancer Fellowship Award
2002 Anima Sen Memorial Award
2007 IISc Alumni Award
2007 BBMP Kempe Gowda Award

Kalappa Muniyappa (born 1952) is an Indian molecular biologist and geneticist, known for his researches on the chromatization of DNA and gene targeting.[1] He is a professor and chairman of the department of biochemistry of the Indian Institute of Science[2] and an elected fellow of the Indian National Science Academy, Indian Academy of Sciences and the National Academy of Sciences, India.[3] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1995, for his contributions to biological sciences.[4]

Biography

Born on 2 February 1951 in the South Indian state of Karnataka, Kalappa Muniyappa, after graduating in science from Mysore University in 1974, secured his master's degree in 1976 from the same university with first rank.[3] His doctoral degree came from the Indian Institute of Science in 1980 after which he did his post-doctoral studies (1981–86) at the University of Georgia and at Yale University School of Medicine[5] and returned to India in 1987 to join the Indian Institute of Science the next year as a member of faculty. He was made a professor in 1999 and is the incumbent chairman of the department of biochemistry of IISc. In between, he held visiting professorship at American Cancer Society, University of Washington, Seattle, Osaka University, University of Sydney and the Medical Research Council, London.[3]

Legacy

Chording mycobacterium tuberculosis culture - luminescent microscope image

Focusing his early researches on the molecular basis of homologous genetic recombination and employing RecA paradigm, Muniyappa demonstrated the effects of chromatization of DNA on homologous pairing and strand exchange and his studies are known to have assisted in exploring ways for gene targeting, cell senescence and genome stability.[6] His studies on chromosome synapsis, genetic recombination and telomere dynamics attempted to widen the understanding of cellular recombination and Holliday junction and he is credited with discovery of a negative regulatory mechanism of homologous recombination.[3] His contributions in deciphering genetic recombination in Mycobacterium tuberculosis are also reported to have influenced further researches on the mechanism of genetic exchange and lateral gene transfer. His researches have been published in a number of articles of which 136 articles have been listed by ResearchGate, an online article repository.[7]

At the Indian Institute of Science, he has set up a laboratory, K. Muniyappa's Lab, to pursue researches in the fields of Cancer biology, Genetics, Biochemistry and Biophysics, where he mentors a number of doctoral and post-doctoral research scholars.[8] It was under his leadership, IISc introduced new academic programs such as Integrated PhD program, Interdisciplinary program in chemical biology and National post-doctoral training program in Biotechnology and Life Sciences and and he has served as their coordinator at inception. A member of the editorial board of the Journal of Molecular Signaling,[9] he has also been associated with Journal of Biosciences and Indian Journal of Biophysics and Biochemistry as their editorial board member and has served as the vice president and secretary of the Society of Biological Chemists.[3]

Awards and honors

Muniyappa received the Hanumantha Rao Memorial Medal of the Dr. NTR University of Health Sciences in 1980 the Rockefeller Foundation Career Development Award in 1992.[3] The Council of Scientific and Industrial Research awarded him the Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards in 1995, the same year as he got the M. Sreenivasaya Memorial Award of the Indian Institute of Science.[10] The American Cancer Society extended the Eleanor Roosevelt Fellowship Award to him in 1995 and he received the Yamagiwa International Cancer Fellowship Award in 1999. The Indian Science Congress Association selected him for the Anima Sen Memorial Award in 2002 and he received two awards in 2007, the Indian Institute of Science Alumnus Award and the Kempe Gowda Award of the Bruhat Bengaluru Mahanagara Palike (BBMP).[3] A founder member of the Karnataka State Academy for Science and Technology, Muniyappa is an elected fellow of the Indian National Science Academy, Indian Academy of Sciences[11] and the National Academy of Sciences, India.[12]

See also

References

  1. ↑ "Brief Profile of the Awardee". Shanti Swarup Bhatnagar Prize. 2016. Retrieved October 5, 2016.
  2. ↑ "K. Muniyappa on IISC". Indian Institute of Science. 2016. Retrieved October 9, 2016.
  3. 1 2 3 4 5 6 7 "Indian fellow - Muniyappa". Indian National Science Academy. 2016. Retrieved October 6, 2016.
  4. ↑ "View Bhatnagar Awardees". Shanti Swarup Bhatnagar Prize. 2016. Retrieved October 5, 2016.
  5. ↑ "Dr. Muniyappa Kalappa on Vidwan". Vidwan. 2016. Retrieved October 9, 2016.
  6. ↑ "Handbook of Shanti Swarup Bhatnagar Prize Winners" (PDF). Council of Scientific and Industrial Research. 1999. p. 32. Retrieved October 5, 2016.
  7. ↑ "Muniyappa on ResearchGate". Author profile. ResearchGate. 2016. Retrieved October 9, 2016.
  8. ↑ "K. Muniyappa's Lab". Indian Institute of Science. 2016. Retrieved October 9, 2016.
  9. ↑ "Editorial board". Journal of Molecular Signaling. 2016. Retrieved October 10, 2016.
  10. ↑ "M. Sreenivasaya Memorial Award". Indian Institute of Science. 2016. Retrieved October 9, 2016.
  11. ↑ "Fellow profile - Muniyappa". Indian Academy of Sciences. 2016. Retrieved October 6, 2016.
  12. ↑ "NASI fellows". National Academy of Sciences, India. 2016. Retrieved October 8, 2016.

External links

Further reading

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