Layilin

LAYN
Identifiers
Aliases	LAYN, Layilin
External IDs	MGI: 2685357 HomoloGene: 18716 GeneCards: LAYN
Genetically Related Diseases
obesity[1]
Orthologs
Species	Human	Mouse
Entrez	143903	244864
Ensembl	ENSG00000204381	ENSMUSG00000060594
UniProt	Q6UX15	Q8C351
RefSeq (mRNA)	NM_001258390 NM_001258391 NM_178834 NM_001318799	NM_001033534
RefSeq (protein)	NP_001245319.1 NP_001245320.1 NP_849156.1 NP_001305728.1	NP_001028706.1
Location (UCSC)	Chr 11: 111.54 – 111.56 Mb	Chr 9: 51.06 – 51.08 Mb
PubMed search	[2]	[3]
Wikidata

View/Edit Human

View/Edit Mouse

Layilin is a protein that in humans is encoded by the LAYN gene.^[4]

References

1. "Diseases that are genetically associated with LAYN view/edit references on wikidata".
2. "Human PubMed Reference:".
3. "Mouse PubMed Reference:".
4. "Entrez Gene: Layilin".

Further reading

• Bono P, Rubin K, Higgins JM, Hynes RO (2001). "Layilin, a novel integral membrane protein, is a hyaluronan receptor". Mol. Biol. Cell. 12 (4): 891–900. doi:10.1091/mbc.12.4.891. PMC 32274. PMID 11294894.
• Borowsky ML, Hynes RO (1998). "Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles". J. Cell Biol. 143 (2): 429–42. doi:10.1083/jcb.143.2.429. PMC 2132847. PMID 9786953.
• Forteza RM, Casalino-Matsuda SM, Falcon NS, Valencia Gattas M, Monzon ME (2012). "Hyaluronan and layilin mediate loss of airway epithelial barrier function induced by cigarette smoke by decreasing E-cadherin". J. Biol. Chem. 287 (50): 42288–98. doi:10.1074/jbc.M112.387795. PMC 3516772. PMID 23048036.
• Bono P, Cordero E, Johnson K, Borowsky M, Ramesh V, Jacks T, Hynes RO (2005). "Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin". Exp. Cell Res. 308 (1): 177–87. doi:10.1016/j.yexcr.2005.04.017. PMID 15913605.