Linopristin

Linopristin
Names
IUPAC name
N-((6R,9S,10R,13S,15aS,22S,24aS)-22-(4-(dimethylamino)benzyl)-6-ethyl-10,23-dimethyl-18-(morpholinomethyl)-5,8,12,15,21,24-hexaoxo-13-phenyl-2,3,5,6,7,8,9,10,12,13,14,15,15a,16,19,21,22,23,24,24a-icosahydro-1H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl)-3-hydroxypicolinamide
Other names
RPR 202698; RPR 202868
Identifiers
325965-23-9 YesY
3D model (Jmol) Interactive image
ECHA InfoCard 100.218.103
UNII 312V80FR4J
Properties
C50H63N9O10
Molar mass 950.11 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Linopristin is an antibiotic of the streptogramin B class. It is one of the components of the antibiotic combination NXL103.[1]

References

  1. Pankuch, Glenn A.; Kelly, Linda M.; Lin, Gengrong; Bryskier, Andre; Couturier, Catherine; Jacobs, Michael R.; Appelbaum, Peter C. (2003). "Activities of a new oral streptogramin, XRP 2868, compared to those of other agents against Streptococcus pneumoniae and Haemophilus species". Antimicrobial Agents and Chemotherapy. 47 (10): 3270–3274. doi:10.1128/AAC.47.10.3270-3274.2003. PMC 201162Freely accessible. PMID 14506040.


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