Lysyltransferase
lysyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.2.3 | ||||||||
CAS number | 37257-20-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a lysyltransferase (EC 2.3.2.3) is an enzyme that catalyzes the chemical reaction
- L-lysyl-tRNA + phosphatidylglycerol tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol
Thus, the two substrates of this enzyme are L-lysyl-tRNA and phosphatidylglycerol, whereas its two products are tRNA and 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol.
This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase.
References
- Lennarz WJ, Bonsen PP, van Deenen LL (1967). "Substrate specificity of O-L-lysylphosphatidylglycerol synthetase Enzymatic studies on the structure of O-L-lysylphosphatidylglycerol". Biochemistry. 6 (8): 2307–12. doi:10.1021/bi00860a005. PMID 6049461.
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