mir-156 microRNA precursor
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| mir-156 microRNA precursor | |
|---|---|
 | |
| Predicted secondary structure and sequence conservation of mir-156 | |
| Identifiers | |
| Symbol | mir-156 |
| Rfam | RF00073 |
| miRBase | MI0000178 |
| miRBase family | MIPF0000008 |
| Other data | |
| RNA type | Gene; miRNA |
| Domain(s) | Eukaryota |
| GO | 0035195 0035068 |
| SO | 0001244 |
MicroRNA (miRNA) precursor mir-156 is a family of plant non-coding RNA. This microRNA has now been predicted or experimentally confirmed in a range of plant species (MIPF0000008). Animal miRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In plants the precursor sequences may be longer, and the carpel factory (caf) enzyme appears to be involved in processing. In this case the mature sequence comes from the 5' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA.
Further reading
- Reinhart, BJ; Weinstein EG; Rhoades MW; Bartel B; Bartel DP (2002). "MicroRNAs in plants". Genes Dev. 16 (13): 1616–1626. doi:10.1101/gad.1004402. PMC 186362
. PMID 12101121. - Ambros, V (2001). "microRNAs: tiny regulators with great potential". Cell. 107 (7): 823–826. doi:10.1016/S0092-8674(01)00616-X. PMID 11779458.
- Zhang B, Pan X (July 2009). "Expression of microRNAs in cotton". Mol. Biotechnol. 42 (3): 269–74. doi:10.1007/s12033-009-9163-y. PMID 19288227.
- Yu, S; Galvão, VC; Zhang, YC; Horrer, D; Zhang, TQ; Hao, YH; Feng, YQ; Wang, S; Schmid, M; Wang, JW (August 2012). "Gibberellin regulates the Arabidopsis floral transition through miR156-targeted SQUAMOSA promoter binding-like transcription factors.". The Plant cell. 24 (8): 3320–32. doi:10.1105/tpc.112.101014. PMID 22942378.