NADH kinase
NADH kinase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC number | 2.7.1.86 | ||||||||
CAS number | 62213-39-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
|
In enzymology, a NADH kinase (EC 2.7.1.86) is an enzyme that catalyzes the chemical reaction
- ATP + NADH ADP + NADPH
Thus, the two substrates of this enzyme are ATP and NADH, whereas its two products are ADP and NADPH.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:NADH 2'-phosphotransferase. Other names in common use include reduced nicotinamide adenine dinucleotide kinase (phosphorylating), DPNH kinase, reduced diphosphopyridine nucleotide kinase, and NADH kinase. This enzyme has at least one activator, acetate.[1]
References
- Griffiths MM, Bernofsky C (1972). "Purification and properties of reduced diphosphopyridine nucleotide kinase from yeast mitochondria". J. Biol. Chem. 247 (5): 1473–8. PMID 4335000.
This article is issued from Wikipedia - version of the 8/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.