NDST3

NDST3
Identifiers
Aliases	NDST3, HSST3, N-deacetylase/N-sulfotransferase 3
External IDs	MGI: 1932544 HomoloGene: 3513 GeneCards: NDST3
Gene ontology Molecular function • transferase activity • sulfotransferase activity • catalytic activity • hydrolase activity • [heparan sulfate-glucosamine N-sulfotransferase activity] Cellular component • integral component of membrane • Golgi membrane • Golgi apparatus • membrane Biological process • metabolic process • heparan sulfate proteoglycan biosynthetic process • heparin biosynthetic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9348	83398
Ensembl	ENSG00000164100	ENSMUSG00000027977
UniProt	O95803	Q9EQH7
RefSeq (mRNA)	NM_004784	NM_001293682 NM_031186
RefSeq (protein)	NP_004775.1	NP_001280611.1 NP_112463.2
Location (UCSC)	Chr 4: 118.03 – 118.26 Mb	Chr 3: 123.53 – 123.69 Mb
PubMed search	[1]	[2]
Wikidata

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Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 is an enzyme that in humans is encoded by the NDST3 gene.^[3][4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Aikawa J, Esko JD (Mar 1999). "Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family". J Biol Chem. 274 (5): 2690–5. doi:10.1074/jbc.274.5.2690. PMID 9915799.
4. "Entrez Gene: NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3".

Further reading

• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Aikawa J, Grobe K, Tsujimoto M, Esko JD (2001). "Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.". J. Biol. Chem. 276 (8): 5876–82. doi:10.1074/jbc.M009606200. PMID 11087757.
• "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Boutry M, Vassarotti A, Ghislain M, et al. (1984). "Isolation of the structural genes for the alpha and beta subunits of the mitochondrial ATPase from the fission yeast Schizosaccharomyces pombe.". J. Biol. Chem. 259 (5): 2840–4. PMID 6230352.