PARC (gene)

CUL9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases CUL9, H7AP1, PARC, 1810035I07Rik, Cul-9, mKIAA0708, cullin 9
External IDs MGI: 1925559 HomoloGene: 56696 GeneCards: CUL9
Genetically Related Diseases
obesity[1]
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

23113

78309

Ensembl

ENSG00000112659

ENSMUSG00000040327

UniProt

Q8IWT3

Q80TT8

RefSeq (mRNA)

NM_015089

NM_001081335

RefSeq (protein)

NP_055904.1

n/a

Location (UCSC) Chr 6: 43.18 – 43.22 Mb Chr 17: 46.5 – 46.55 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

Cullin-9 is a protein that in humans is encoded by the CUL9 gene.[4][5][6][7]

Interactions

PARC (gene) has been shown to interact with P53.[6]

References

  1. "Diseases that are genetically associated with CUL9 view/edit references on wikidata".
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. Skaar JR, Florens L, Tsutsumi T, Arai T, Tron A, Swanson SK, Washburn MP, DeCaprio JA (Mar 2007). "PARC and CUL7 form atypical cullin RING ligase complexes". Cancer Res. 67 (5): 2006–14. doi:10.1158/0008-5472.CAN-06-3241. PMID 17332328.
  5. Moynihan TP, Ardley HC, Nuber U, Rose SA, Jones PF, Markham AF, Scheffner M, Robinson PA (Nov 1999). "The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1". J Biol Chem. 274 (43): 30963–8. doi:10.1074/jbc.274.43.30963. PMID 10521492.
  6. 1 2 Nikolaev AY, Li M, Puskas N, Qin J, Gu W (Jan 2003). "Parc: a cytoplasmic anchor for p53". Cell. 112 (1): 29–40. doi:10.1016/S0092-8674(02)01255-2. PMID 12526791.
  7. "Entrez Gene: PARC p53-associated parkin-like cytoplasmic protein".

Further reading


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