Pirenoxine
Clinical data | |
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Trade names | Catalin |
ATCvet code | QS01XA91 (WHO) |
Identifiers | |
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CAS Number | 1043-21-6 |
PubChem (CID) | 4846 |
ChemSpider | 4846 |
UNII | 27L0EP6IZK |
ECHA InfoCard | 100.012.612 |
Chemical and physical data | |
Formula | C16H8N2O5 |
Molar mass | 308.24512 g/mol |
3D model (Jmol) | Interactive image |
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Pirenoxine (abbreviated PRX, trade name Catalin) is a medication used in the possible treatment and prevention of cataracts. A report in the journal of Inorganic Chemistry showed that in liquid solutions pirenoxine could cause decreased cloudiness of a crystallin solution produced to mimic the environment of the eye. Pirenoxine interacts with selenite or calcium ions that have been proven as factors leading to the formation of lens cataract.[1]
Pirenoxine reduces the cloudiness of the lens solution containing calcium by 38% and reduced the cloudiness of the selenite solution by 11%.
References
- ↑ Liao, J. H.; Chen, C. S.; Hu, C. C.; Chen, W. T.; Wang, S. P.; Lin, I. L.; Huang, Y. H.; Tsai, M. H.; Wu, T. H.; Huang, F. Y.; Wu, S. H. (2011). "Ditopic Complexation of Selenite Anions or Calcium Cations by Pirenoxine: An Implication for Anti-Cataractogenesis". Inorganic Chemistry. 50 (1): 365–377. doi:10.1021/ic102151p. PMID 21138325.
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