RAB35

RAB35
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3TW8
Identifiers
Aliases	RAB35, H-ray, RAB1C, RAY, member RAS oncogene family
External IDs	MGI: 1924657 HomoloGene: 21361 GeneCards: RAB35
Gene ontology Molecular function • nucleotide binding • GDP binding • GTP binding • protein binding • GTPase activity • phosphatidylinositol-4,5-bisphosphate binding Cellular component • endosome • endoplasmic reticulum membrane • membrane • melanosome • clathrin-coated endocytic vesicle • Golgi membrane • plasma membrane • mitochondrion • cell projection membrane • intercellular bridge • clathrin-coated pit • endosome membrane • extracellular exosome • cytoplasmic vesicle • clathrin-coated vesicle • intracellular Biological process • protein localization • cellular response to nerve growth factor stimulus • antigen processing and presentation • small GTPase mediated signal transduction • cytokinesis • endosomal transport • ER to Golgi vesicle-mediated transport • plasma membrane to endosome transport • endocytic recycling • transport • protein transport • protein localization to endosome • neuron projection development Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11021	77407
Ensembl	ENSG00000111737	ENSMUSG00000029518
UniProt	Q15286	Q6PHN9
RefSeq (mRNA)	NM_001167606 NM_006861	NM_198163
RefSeq (protein)	NP_001161078.1 NP_006852.1	NP_937806.1
Location (UCSC)	Chr 12: 120.1 – 120.12 Mb	Chr 5: 115.63 – 115.65 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Ras-related protein Rab-35 is a protein that in humans is encoded by the RAB35 gene.^[3] This GTPase participates in the traffic of recycling endosomes toward the plasma membrane,^[4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: RAB35 RAB35, member RAS oncogene family".
4. Kouranti I, Sachse M, Arouche N, Goud B, Echard A (Sep 2006). "Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis". Current Biology. 16 (17): 1719–25. doi:10.1016/j.cub.2006.07.020. PMID 16950109.

Further reading

• Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF (Nov 2006). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes". Journal of Proteome Research. 5 (11): 3135–44. doi:10.1021/pr060363j. PMID 17081065.
• Kouranti I, Sachse M, Arouche N, Goud B, Echard A (Sep 2006). "Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis". Current Biology. 16 (17): 1719–25. doi:10.1016/j.cub.2006.07.020. PMID 16950109.
• Abe Y, Takeuchi T, Imai Y, Murase R, Kamei Y, Fujibuchi T, Matsumoto S, Ueda N, Ogasawara M, Shigemoto K, Kito K (May 2006). "A Small Ras-like protein Ray/Rab1c modulates the p53-regulating activity of PRPK". Biochemical and Biophysical Research Communications. 344 (1): 377–85. doi:10.1016/j.bbrc.2006.03.071. PMID 16600182.
• Zhu AX, Zhao Y, Flier JS (Dec 1994). "Molecular cloning of two small GTP-binding proteins from human skeletal muscle". Biochemical and Biophysical Research Communications. 205 (3): 1875–82. doi:10.1006/bbrc.1994.2889. PMID 7811277.