RAB6B

RAB6B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2E9S, 2FE4, 2FFQ
Identifiers
Aliases	RAB6B
External IDs	MGI: 107283 HomoloGene: 39749 GeneCards: RAB6B
Genetically Related Diseases
smallpox[1]
Gene ontology Molecular function • nucleotide binding • GTP binding • GTPase activity • myosin V binding • protein binding Cellular component • Golgi apparatus • Golgi membrane • membrane • cytoplasmic vesicle • endoplasmic reticulum-Golgi intermediate compartment • cytoplasmic, membrane-bounded vesicle • cytosol • intracellular Biological process • retrograde vesicle-mediated transport, Golgi to ER • protein transport • small GTPase mediated signal transduction • intra-Golgi vesicle-mediated transport • retrograde transport, endosome to Golgi • transport • vesicle-mediated transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51560	270192
Ensembl	ENSG00000154917	ENSMUSG00000032549
UniProt	Q9NRW1	P61294
RefSeq (mRNA)	NM_016577	NM_173781
RefSeq (protein)	NP_057661.3	NP_776142.1
Location (UCSC)	Chr 3: 133.82 – 133.9 Mb	Chr 9: 103.11 – 103.19 Mb
PubMed search	[2]	[3]
Wikidata

View/Edit Human

View/Edit Mouse

Ras-related protein Rab-6B is a protein that in humans is encoded by the RAB6B gene.^[4]

References

1. "Diseases that are genetically associated with RAB6B view/edit references on wikidata".
2. "Human PubMed Reference:".
3. "Mouse PubMed Reference:".
4. "Entrez Gene: RAB6B RAB6B, member RAS oncogene family".

Further reading

• Chen D, Guo J, Gahl WA (January 1997). "RAB GTPases expressed in human melanoma cells". Biochimica et Biophysica Acta. 1355 (1): 1–6. doi:10.1016/S0167-4889(96)00169-3. PMID 9030196.
• Opdam FJ, Echard A, Croes HJ, van den Hurk JA, van de Vorstenbosch RA, Ginsel LA, Goud B, Fransen JA (August 2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus". Journal of Cell Science. 113 ( Pt 15) (15): 2725–35. PMID 10893188.
• Monier S, Jollivet F, Janoueix-Lerosey I, Johannes L, Goud B (April 2002). "Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport". Traffic. 3 (4): 289–97. doi:10.1034/j.1600-0854.2002.030406.x. PMID 11929610.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Garcia-Saez I, Tcherniuk S, Kozielski F (July 2006). "The structure of human neuronal Rab6B in the active and inactive form". Acta Crystallographica Section D. 62 (Pt 7): 725–33. doi:10.1107/S0907444906015319. PMID 16790928.
• Wanschers BF, van de Vorstenbosch R, Schlager MA, Splinter D, Akhmanova A, Hoogenraad CC, Wieringa B, Fransen JA (October 2007). "A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells". Experimental Cell Research. 313 (16): 3408–20. doi:10.1016/j.yexcr.2007.05.032. PMID 17707369.