RGS11

RGS11
Identifiers
Aliases RGS11, RS11, regulator of G-protein signaling 11
External IDs MGI: 1354739 HomoloGene: 77719 GeneCards: RGS11
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

8786

50782

Ensembl

ENSG00000076344

ENSMUSG00000024186

UniProt

O94810

Q9Z2H1

RefSeq (mRNA)

NM_001286485
NM_001286486
NM_003834
NM_183337

NM_001081069

RefSeq (protein)

NP_001273414.1
NP_001273415.1
NP_003825.1
NP_899180.1

n/a

Location (UCSC) Chr 16: 0.27 – 0.28 Mb Chr 17: 26.2 – 26.21 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Regulator of G-protein signaling 11 is a protein that in humans is encoded by the RGS11 gene.[3][4]

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.[4]

References

Further reading


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