Respirovirus
Respirovirus | |
---|---|
Virus classification | |
Group: | Group V ((-)ssRNA) |
Order: | Mononegavirales |
Family: | Paramyxoviridae |
Genus: | Respirovirus |
Type species | |
Sendai virus | |
Species | |
Bovine parainfluenza virus 3 |
Respirovirus is a genus of viruses in the order Mononegavirales, in the family Paramyxoviridae. Rodents and human serve as natural hosts. There are currently five species in this genus including the type species Sendai virus. Diseases associated with this genus include: acute febrile respiratory tract infection.[1][2]
Taxonomy
Genus | Species | Virus (Abbreviation) |
Respirovirus | Bovine parainfluenza virus 3 | bovine parainfluenza virus 3 (BPIV-3) |
Human parainfluenza virus 1 | human parainfluenza virus 1 (HPIV-1) | |
Human parainfluenza virus 3 | human parainfluenza virus 3 (HPIV-3) | |
Porcine parainfluenzavirus 1 | porcine parainfluenza virus 1 (PPIV-1) | |
Sendai virus* | Sendai virus (SeV) | |
Table legend: "*" denotes type species.
Structure
Respirovirions are enveloped, with spherical geometries. The diameter is around 150 nm. Respirovirus genomes are linear, around 15kb in length. The genome codes for 8 proteins.[1]
Genus | Structure | Symmetry | Capsid | Genomic Arrangement | Genomic Segmentation |
---|---|---|---|---|---|
Respirovirus | Spherical | Enveloped | Linear | Monopartite |
Life Cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaches to host cell. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. Translation takes place by leaky scanning, and ribosomal shunting. The virus exits the host cell by budding. Rodents and human serve as the natural host. Transmission routes are respiratory.[1]
Genus | Host Details | Tissue Tropism | Entry Details | Release Details | Replication Site | Assembly Site | Transmission |
---|---|---|---|---|---|---|---|
Respirovirus | Rodents; humans | None | Glycoprotein | Budding | Cytoplasm | Cytoplasm | Aerosols |
References
- 1 2 3 "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ↑ ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015.
- ↑ Afonso, Claudio L.; Amarasinghe, Gaya K.; Bányai, Krisztián; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Bejerman, Nicolás; Blasdell, Kim R.; Briand, François-Xavier (2016-08-01). "Taxonomy of the order Mononegavirales: update 2016". Archives of Virology. 161 (8): 2351–2360. doi:10.1007/s00705-016-2880-1. ISSN 1432-8798. PMC 4947412. PMID 27216929.