SFRS2

SRSF2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases SRSF2, PR264, SC-35, SC35, SFRS2, SFRS2A, SRp30b, serine/arginine-rich splicing factor 2, serine and arginine rich splicing factor 2
External IDs MGI: 98284 HomoloGene: 37721 GeneCards: SRSF2
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

6427

20382

Ensembl

ENSG00000161547

ENSMUSG00000034120

UniProt

Q01130

Q62093

RefSeq (mRNA)

NM_001195427
NM_003016

NM_011358

RefSeq (protein)

NP_001182356.1
NP_003007.2

NP_035488.1

Location (UCSC) Chr 17: 76.73 – 76.74 Mb Chr 11: 116.85 – 116.85 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Splicing factor, arginine/serine-rich 2 is a protein that in humans is encoded by the SFRS2 gene.[3][4][5]

Interactions

SFRS2 has been shown to interact with CDC5L[6] and ASF/SF2.[7]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Bermingham JR Jr; Arden KC; Naumova AK; Sapienza C; Viars CS; Fu XD; Khotz J; Manley JL; Rosenfeld MG (February 1996). "Chromosomal localization of mouse and human genes encoding the splicing factors ASF/SF2 (SFRS1) and SC-35 (SFRS2)". Genomics. 29 (1): 70–9. doi:10.1006/geno.1995.1216. PMID 8530103.
  4. Fu XD; Maniatis T (May 1992). "Isolation of a complementary DNA that encodes the mammalian splicing factor SC35". Science. 256 (5056): 535–8. doi:10.1126/science.1373910. PMID 1373910.
  5. "Entrez Gene: SFRS2 splicing factor, arginine/serine-rich 2".
  6. Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. ENGLAND. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846Freely accessible. PMID 11101529.
  7. Zhang, W J; Wu J Y (October 1996). "Functional properties of p54, a novel SR protein active in constitutive and alternative splicing". Mol. Cell. Biol. UNITED STATES. 16 (10): 5400–8. ISSN 0270-7306. PMC 231539Freely accessible. PMID 8816452.

Further reading


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