SH2
SH2 may stand for:
- Silent Hill 2, a 2001 survival horror video game published by Konami
- SH2 domain (Src Homology 2), a protein domain within the Src oncoprotein
- SH-2, an iteration of the SuperH CPU core developed by Hitachi
- SH-2 Seasprite, an American-built ship-based helicopter
- SH-2G Super Seasprite, an American-built ship-based helicopter
- Shadow Hearts: Covenant, also known as Shadow Hearts II
- State Highway 2, see List of highways numbered 2, a common highway name in many countries
- Hydrogen sulfide
- SH2, one of three classifications of participants in Paralympic shooting events
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