SLMAP

SLMAP
Identifiers
Aliases	SLMAP, SLAP, sarcolemma associated protein
External IDs	MGI: 1933549 HomoloGene: 31428 GeneCards: SLMAP
Genetically Related Diseases
obesity[1]
Gene ontology Molecular function • protein binding Cellular component • smooth endoplasmic reticulum • cytoplasm • integral component of membrane • sarcolemma • plasma membrane • integral component of plasma membrane • cytoskeleton • membrane • microtubule organizing center Biological process • muscle contraction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7871	83997
Ensembl	ENSG00000163681	ENSMUSG00000021870
UniProt	Q14BN4	Q3URD3
RefSeq (mRNA)	NM_001304420 NM_001304421 NM_001304422 NM_001304423 NM_001311178 NM_001311179 NM_007159	NM_032008 NM_001310445
RefSeq (protein)	NP_001291349.1 NP_001291350.1 NP_001298107.1 NP_001298108.1 NP_009090.2	NP_001297374.1 NP_114397.3
Location (UCSC)	Chr 3: 57.76 – 57.93 Mb	Chr 14: 26.41 – 26.53 Mb
PubMed search	[2]	[3]
Wikidata

View/Edit Human

View/Edit Mouse

Sarcolemmal membrane-associated protein is a protein that in humans is encoded by the SLMAP gene.^[4][5][6]

Interactions

SLMAP has been shown to interact with STK24.^[7][8]

References

1. "Diseases that are genetically associated with SLMAP view/edit references on wikidata".
2. "Human PubMed Reference:".
3. "Mouse PubMed Reference:".
4. Wigle JT, Demchyshyn L, Pratt MA, Staines WA, Salih M, Tuana BS (December 19, 1997). "Molecular cloning, expression, and chromosomal assignment of sarcolemmal-associated proteins. A family of acidic amphipathic alpha-helical proteins associated with the membrane". J. Biol. Chem. 272 (51): 32384–94. doi:10.1074/jbc.272.51.32384. PMID 9405447.
5. Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
6. "Entrez Gene: SLMAP sarcolemma associated protein".
7. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
8. Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Mol. Cell Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.

Further reading

• Wielowieyski PA, Sevinc S, Guzzo R, Salih M, Wigle JT, Tuana BS (2000). "Alternative splicing, expression, and genomic structure of the 3' region of the gene encoding the sarcolemmal-associated proteins (SLAPs) defines a novel class of coiled-coil tail-anchored membrane proteins". J. Biol. Chem. 275 (49): 38474–81. doi:10.1074/jbc.M007682200. PMID 10986292.
• Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O (2000). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.