SULT1A2

SULT1A2
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
Aliases SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2, sulfotransferase family 1A member 2
External IDs HomoloGene: 128920 GeneCards: SULT1A2
Orthologs
Species Human Mouse
Entrez

6799

n/a

Ensembl

ENSG00000197165

n/a

UniProt

P50226

n/a

RefSeq (mRNA)

NM_001054
NM_177528

n/a

RefSeq (protein)

NP_001045.1
NP_803564.1

n/a

Location (UCSC) Chr 16: 28.59 – 28.6 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Sulfotransferase 1A2 is an enzyme that in humans is encoded by the SULT1A2 gene.[2][3][4]

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described.[4]

References

  1. "Human PubMed Reference:".
  2. Her C, Raftogianis R, Weinshilboum RM (Sep 1996). "Human phenol sulfotransferase STP2 gene: molecular cloning, structural characterization, and chromosomal localization". Genomics. 33 (3): 409–20. doi:10.1006/geno.1996.0216. PMID 8661000.
  3. Dooley TP, Huang Z (Dec 1996). "Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16". Biochem Biophys Res Commun. 228 (1): 134–40. doi:10.1006/bbrc.1996.1628. PMID 8912648.
  4. 1 2 "Entrez Gene: SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2".

Further reading


This article is issued from Wikipedia - version of the 6/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.