TESK2

TESK2
Identifiers
Aliases TESK2
External IDs MGI: 2385204 HomoloGene: 5188 GeneCards: TESK2
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

10420

230661

Ensembl

ENSG00000070759

ENSMUSG00000033985

UniProt

Q96S53

Q8VCT9

RefSeq (mRNA)

NM_007170
NM_001320800

NM_146151

RefSeq (protein)

NP_009101.2
NP_001307729.1

NP_666263.3

Location (UCSC) Chr 1: 45.34 – 45.49 Mb Chr 4: 116.72 – 116.81 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Dual specificity testis-specific protein kinase 2 is an enzyme that in humans is encoded by the TESK2 gene.[3][4]

Function

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meiotic stages and/or early stages of spermiogenesis.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Røsok O, Pedeutour F, Ree AH, Aasheim HC (October 1999). "Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis". Genomics. 61 (1): 44–54. doi:10.1006/geno.1999.5922. PMID 10512679.
  4. 1 2 "Entrez Gene: TESK2 testis-specific kinase 2".

Further reading


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