TGS1

TGS1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases TGS1, NCOA6IP, PIMT, PIPMT, trimethylguanosine synthase 1
External IDs MGI: 2151797 HomoloGene: 32608 GeneCards: TGS1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

96764

116940

Ensembl

ENSG00000137574

ENSMUSG00000028233

UniProt

Q96RS0

Q923W1

RefSeq (mRNA)

NM_024831
NM_001317902

NM_054089

RefSeq (protein)

NP_079107.6
NP_001304831.1

NP_473430.3

Location (UCSC) Chr 8: 55.77 – 55.83 Mb Chr 4: 3.57 – 3.62 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Trimethylguanosine synthase is an enzyme that in humans is encoded by the TGS1 gene.[3][4][5]

Interactions

TGS1 has been shown to interact with:

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. 1 2 Zhu Y, Qi C, Cao WQ, Yeldandi AV, Rao MS, Reddy JK (Aug 2001). "Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function". Proc Natl Acad Sci U S A. 98 (18): 10380–5. doi:10.1073/pnas.181347498. PMC 56969Freely accessible. PMID 11517327.
  4. Mouaikel J, Verheggen C, Bertrand E, Tazi J, Bordonné R (May 2002). "Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus". Mol Cell. 9 (4): 891–901. doi:10.1016/S1097-2765(02)00484-7. PMID 11983179.
  5. "Entrez Gene: TGS1 trimethylguanosine synthase homolog (S. cerevisiae)".
  6. 1 2 3 4 Misra P, Qi C, Yu S, Shah SH, Cao WQ, Rao MS, Thimmapaya B, Zhu Y, Reddy JK (May 2002). "Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation". J. Biol. Chem. 277 (22): 20011–9. doi:10.1074/jbc.M201739200. PMID 11912212.
  7. Enünlü I, Pápai G, Cserpán I, Udvardy A, Jeang KT, Boros I (Sep 2003). "Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localizes to the cytoplasm and nucleus". Biochem. Biophys. Res. Commun. 309 (1): 44–51. doi:10.1016/s0006-291x(03)01514-6. PMID 12943661.

Further reading


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