Thrombospondin 4

THBS4
Identifiers
Aliases THBS4, TSP4, TSP-4, thrombospondin 4
External IDs MGI: 1101779 HomoloGene: 20691 GeneCards: THBS4
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

7060

21828

Ensembl

ENSG00000113296

ENSMUSG00000021702

UniProt

P35443

Q9Z1T2

RefSeq (mRNA)

NM_001306212
NM_001306213
NM_001306214
NM_003248

NM_011582

RefSeq (protein)

NP_001293141.1
NP_001293142.1
NP_001293143.1
NP_003239.2

NP_035712.1

Location (UCSC) Chr 5: 79.99 – 80.08 Mb Chr 13: 92.75 – 92.79 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Thrombospondin-4 is a protein that in humans is encoded by the THBS4 gene.[3][4]

The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. Studies of the rat counterpart suggest that this protein may be involved in local signaling in the developing and adult nervous system.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Lawler J, McHenry K, Duquette M, Derick L (Mar 1995). "Characterization of human thrombospondin-4". J Biol Chem. 270 (6): 2809–14. doi:10.1074/jbc.270.6.2809. PMID 7852353.
  4. 1 2 "Entrez Gene: THBS4 thrombospondin 4".

Further reading


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