Toxoflavin
Names | |
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IUPAC name
1,6-Dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione | |
Other names
Toxoflavine; Xanthothricin; Xanthotricin | |
Identifiers | |
84-82-2 | |
3D model (Jmol) | Interactive image |
ChEMBL | ChEMBL578512 |
ChemSpider | 59912 |
ECHA InfoCard | 100.213.079 |
PubChem | 66541 |
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Properties | |
C7H7N5O2 | |
Molar mass | 193.17 g·mol−1 |
Appearance | Bright yellow solid |
Melting point | 172 to 173 °C (342 to 343 °F; 445 to 446 K) (decomposes) |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
1.7 mg/kg (IV, mouse) 8.4 mg/kd (oral, mouse) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Toxoflavin is a toxin produced by a variety of bacteria including Burkholderia gladioli. It also has antibiotic properties.[3]
Toxoflavin acts as a pH indicator, changing between yellow and colorless at pH 10.5.[1]
References
- 1 2 Merck Index, 11th Edition, 9480
- ↑ Toxoflavin, at the Comparative Toxicogenomics Database
- ↑ Machlowitz, Roy A.; Fisher, W. P.; McKay, Betsey S.; Tytell, Alfred A.; Charney, Jesse (1954). "Xanthothricin, a new antibiotic". Antibiotics and Chemotherapy. 4: 259–261.
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