Trans-pentaprenyltranstransferase

trans-pentaprenyltranstransferase
Identifiers
EC number 2.5.1.33
CAS number 83745-07-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a trans-pentaprenyltranstransferase (EC 2.5.1.33) is an enzyme that catalyzes the chemical reaction

all-trans-pentaprenyl diphosphate + isopentenyl diphosphate diphosphate + all-trans-hexaprenyl diphosphate

Thus, the two substrates of this enzyme are all-trans-pentaprenyl diphosphate and isopentenyl diphosphate, whereas its two products are diphosphate and all-trans-hexaprenyl diphosphate.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase. Other names in common use include all-trans-hexaprenyl-diphosphate synthase, hexaprenyl diphosphate synthase, and hexaprenyl pyrophosphate synthetase. This enzyme participates in biosynthesis of steroids.

References


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