Tryptophan synthase (indole-salvaging)

Tryptophan synthase (indole-salvaging)
Identifiers
EC number 4.2.1.122
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Tryptophan synthase (indole-salvaging) (EC 4.2.1.122, tryptophan synthase beta2) is an enzyme with systematic name L-serine hydro-lyase (adding indole, L-tryptophan-forming).[1] This enzyme catalyses the following chemical reaction

L-serine + indole L-tryptophan + H2O

This enzyme salvages the lost indole to L-tryptophan.

References

  1. Hettwer, S.; Sterner, R. (2002). "A novel tryptophan synthase β-subunit from the hyperthermophile Thermotoga maritima. Quaternary structure, steady-state kinetics, and putative physiological role". J. Biol. Chem. 277: 8194–8201. doi:10.1074/jbc.m111541200. PMID 11756459.
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