UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase

Thus, the two substrates of this enzyme are UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose and 2-oxoglutarate, whereas its two products are UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase. Other names in common use include uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose, and aminotransferase. It employs one cofactor, pyridoxal phosphate.

References

Distler J, Kaufman B, Roseman S (1966). "Enzymic synthesis of a diamino sugar nucleotide by extracts of type XIV Diplococcus pneumoniae". Arch. Biochem. Biophys. 116 (1): 466–78. doi:10.1016/0003-9861(66)90054-3. PMID 4381351.

Transferase: nitrogenous groups (EC 2.6)

2.6.1: Transaminases	Aspartate transaminase GOT1 GOT2 Alanine transaminase GABA transaminase Tyrosine aminotransferase Ornithine aminotransferase Branched chain aminotransferase Alanine—glyoxylate transaminase AGXT

2.6.3: Oximinotransferases	Oximinotransferase

2.6.99: Other	Pyridoxine 5'-phosphate synthase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

This article is issued from Wikipedia - version of the 8/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.