3,4-Dihydroxystyrene
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Clinical data | |
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ATC code | none |
Legal status | |
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Identifiers | |
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CAS Number |
6053-02-7 ![]() |
PubChem (CID) | 151398 |
ChemSpider |
133430 ![]() |
UNII |
28C0I29E70 ![]() |
KEGG |
C06224 ![]() |
Chemical and physical data | |
Formula | C8H8O2 |
Molar mass | 136.15 g/mol |
3D model (Jmol) | Interactive image |
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3,4-Dihydroxystyrene (DHS) is a centrally-acting inhibitor of the enzyme phenylalanine hydroxylase (PH).[1] It is likely that DHS and other PH inhibitors will never have clinical applications on account of their capacity for inducing hyperphenylalaninemia and phenylketonuria.
See also
References
- ↑ Koizumi S; Matsushima Y; Nagatsu T; Iinuma H; Takeuchi T; Umezawa H (September 1984). "3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases". Biochimica et Biophysica Acta. 789 (2): 111–8. doi:10.1016/0167-4838(84)90194-8. PMID 6148105.
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