C9orf86

RABL6
Identifiers
Aliases	RABL6, C9orf86, PARF, RBEL1, pp8875, RAB, member RAS oncogene family-like 6
External IDs	MGI: 2442633 HomoloGene: 11674 GeneCards: RABL6
Gene ontology Molecular function • nucleotide binding • GTP binding • protein binding Cellular component • cytoplasm • nucleus • intracellular Biological process • small GTPase mediated signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55684	227624
Ensembl	n/a	ENSMUSG00000015087
UniProt	Q3YEC7	Q5U3K5
RefSeq (mRNA)	NM_024718 NM_001173988 NM_001173989 NM_017995	NM_001024616
RefSeq (protein)	NP_001167459.1 NP_001167460.1 NP_078994.3	NP_001019787.2
Location (UCSC)	Chr 9: 136.81 – 136.96 Mb	Chr 2: 25.58 – 25.61 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Putative GTP-binding protein Parf is a protein that in humans is encoded by the C9orf86 gene.^[3][4][5][6]

Interactions

C9orf86 has been shown to interact with MDFI.^[7]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Tompkins V, Hagen J, Zediak VP, Quelle DE (Mar 2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. doi:10.4161/cc.5.6.2560. PMID 16582619.
4. Montalbano J, Jin W, Sheikh MS, Huang Y (Dec 2007). "RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer". The Journal of Biological Chemistry. 282 (52): 37640–9. doi:10.1074/jbc.M704760200. PMID 17962191.
5. Montalbano J, Lui K, Sheikh MS, Huang Y (Jul 2009). "Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation". The Journal of Biological Chemistry. 284 (27): 18129–42. doi:10.1074/jbc.M109.009597. PMC 2709392. PMID 19433581.
6. "Entrez Gene: C9orf86 chromosome 9 open reading frame 86".
7. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Further reading

• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Cui YP, Wang JB, Zhang XY, Bi MX, Guo LP, Lu SH (Sep 2003). "Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene". World Journal of Gastroenterology. 9 (9): 1892–6. PMID 12970870.
• Cui Y, Wang J, Zhang X, Lang R, Bi M, Guo L, Lu SH (Mar 2003). "ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis". Biochemical and Biophysical Research Communications. 302 (4): 904–15. doi:10.1016/S0006-291X(03)00122-0. PMID 12646258.